Structural Speciation Studies in the Binary Al(III)-Quinic Acid Aqueous System

Authors:
M. Daskalakis, C. Mateescu, A. Salifoglou
Abstract:
The importance of aqueous aluminum chemistry in biology relates to Al(III) involvement in many neurological disorders such as Alzheimer’s disease (AD). The biotoxic role of this metal in neurodegeneration is widely researched nowadays with as yet ambiguous results. Therefore, the study of the aqueous chemistry of Al(III) with physiological ligands simulating proteins or peptides in the biological target area is important. An example of such a ligand is quinic acid. We have been able to synthesize, isolate and characterize the first Al(III)–quinic acid complex, K[Al(C7H11O6)3].(OH) .5H2O, from aqueous media.
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