Current issues in xenobiochemistry related to cumulative processes of chemical xenobiotics and pathobiochemistry - review


Zeno Gârban, Mirela Ahmadi-Vincu, Nicoleta-Gabriela Hădărugă, Robert Ujhelyi, Florin Muselin

Volume 28, Issue 3;
Pages: 249-254; 2022
ISSN: 2069-0053 (print) (former ISSN: 1453-1399), Agroprint;
ISSN (online): 2068-9551


Xenobiochemistry, often considered as a subsequent domain of biochemistry, demanded attention due to its aspects of theoretic and applicative interest. Among them, the particularities of biochemical interactions and the extension towards biochemical pathology are distinguished. Its areas of interest include foods (with the risk of contamination), pharmaceutical products, and obviously products of strictly toxic interest (biocides).

An essential aspect in case of xenobiotics of food, pharmaceutical or strictly toxic interest is represented by their specificity to cumulate in the organisms. With reference to the cumulative features, it is mentioned that nowadays the levels of bioaccumulation, bioconcentration, biomagnification are being discussed more and more frequently, like in this work.

Obviously, the diversification of the chemical composition of xenobiotics, the expansion of technologies that can generate more xenobioderivatives, the difficulties sometimes introduced in verifying the traceability of raw materials (in food and pharmaceutical industry), gradually lead to the need of more in depth studies regarding pathobiochemistry with extension to pathophysiology.

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