Brewer s spent grain (BSG) is a beer industry residue that represents more than 85% of the total produced by-products but at the same time it is a valuable source of of dietary fibre, protein and essential amino acids, minerals, polyphenols, vitamins and lipids. The main objective of the study is the obtaining of a traditional smoked sausage incorporating brewer’s spent grain powder, establishing some correlations between storage conditions and sensory and physico-chemical characterization of the product. The substitution of meat pork with 5%, 10%, 15% brewer’s spent grain powder resulted in smoked sausages formulations with enhance nutritional value. The overall acceptability scores for the control and the smoked sausages with BSG were 7.48 and 7.63–6.10 on a nine-point scale, respectively.