Free radicals biogenesis is of interest both for the metabolism of nutrients in biochemistry and for the biotransformation of chemical xenobiotics in xenobiochemistry. The perfection of the physico-chemical methods of investigation allowed the evaluation of the harmful effects induced by the free radicals having as target to find more effective investigations of some important biomarkers in the biochemistry and pathobiochemistry. A brief presentation of these issues in the form of a review is followed in this paper. In a context regarding the harmful effects of free radicals it is mentioned the pro-oxidant and anti-oxidant effects. There are also mentioned the delayed consequences of the of free oxygen radicals action in the appearance of degenerative diseases, ischemic diseases a.o. consequent to oxidative stress, knowing the protective activity of some food antioxidants.
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