Scientific activity in the field of oenology became more intense over time, being necessary regarding the quality of grapes and hence of wine. Recent proofs show that red wine has health benefits, and one in charge could be resveratrol. Moreover, there is evidence that resveratrol has chemo preventive activity against cardiovascular diseases and a variety of cancers. Given these, in this paper we intended to study the variation of resveratrol content in 8 samples of wines from different vineyards from Romania (Dealu Mare, Murfatlar respectively Recaș) which were differently packed in different years. Trans-resveratrol was quantified using a HPLC method, and it ranged from 0.728 to 14.131 mg L-1. Eventually, Merlot variety had the highest concentrations of resveratrol of all wine samples.