The chemistry of vanadium with amino acids and their derivatives. Relevance to health and disease

Athanasios Salifoglou

Volume 17, Issue 2;
Pages: 130-133;
ISSN: 2069-0053 (print) (former: ISSN:1453-1399), Agroprint;
ISSN (online):2068 – 9551
Vanadium is a highly acclaimed chemical element in the chemistry and biology of eukaryotic organisms. Outstanding among the various functions of that elements at different oxidation states stand the antitumorigenic and insulin mimetic activities. The latter reactivity acquires special interest in the case of the human disease of Diabetes mellitus II. IN an effort to explore the potential chemical reactivity of vanadium in the presence of physiological amino acids and the biologically important hydrogen peroxide, research efforts were launched to investigate the potential structural speciation of ternary systems of that element with the aforementioned reagents. The emerging ternary species exhibit unique composition and structures, the physicochecmial properties of which suggest a diverse chemistry in the framework of biological insulin mimetic activity.
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