The study was conducted to assess the impact of the changes in the milk collection two systems – small farms – the “semi-modern production system” and family farms or domestic farms – the “traditional production system” in the Cluj region (from twice daily collection to once, introduction of chilling facilities to the collection and transportation of milk to the processing plant in insulated truck instead of in metal churns at ambient temperature) on the microbial load and antimicrobial residue quality of the milk as well as the temperature and pH of milk, using standard methods. Milk quality is a broad concept that generally encompasses composition, hygiene and the addition of chemical substances or water. The demands on quality can vary, and depend on the end use of the milk. Hygienic quality is naturally of great importance, since bacterial growth in milk during storage can be a health hazard for the consumer and can cause changes in milk composition through enzymatic activity.