Food supplements and the issues related to them are important due to their current use for health maintenance and optimizing. Nowadays the foods that comprise the human diet is more often depleted of the normal levels of micronutrients and therefore cannot maintain the physiological balance, most rigorously the «biochemical homeostasis» which defines the health status. Therefore food supplements can be used to complement the normal diet and insure the necessary levels of nutrients. Food supplements are also administered in order to optimize health status in convalescence. A general study regarding the manufactured and marketed food supplements in Romania was performed in each county and grouped on historical regions: Banat, Moldavia, Muntenia, and Ardeal. This paper will present data regarding food supplements status in Muntenia region which comprises the counties: Argeş, Braşov, Brăila, Buzău, Călăraşi, Constanţa, Dâmboviţa, Dolj, Giurgiu, Gorj, Ialomiţa, Ilfov, Mehedinţi, Olt, Prahova, Teleorman, Tulcea, Vâlcea and the capital Bucharest. The food supplement providers from the Muntenia region were identified and some of the supplements were selected for this study.