This paper presents an antioxidant activity evaluation of aqueous and alcoholic Chelidonium majus L. extracts by using the DPPH method. The whole raw celandine plant was extracted with water or ethanolic solution (in various concentrations) at room temperature or at reflux and the spectrophotometric time scan in the presence of DPPH solution was done. The best antioxidant activity was obtained for concentrated ethanol hot extracts and diluted ethanol cold extracts, the mean DPPH reaction rate being in the range of 0.5-3 µM/s.