Study of the Interaction of the Neurotoxin Al(III) with Quinic Acid

Catherine Gabriel, Melita Menelaou, A. Salifoglou
The importance of aqueous aluminum chemistry in biology relates to Al(III) involvement in many neurological disorders such as Alzheimer’s disease (AD). The biotoxic role of this metal in neurodegeneration is widely researched nowadays with as yet ambiguous results. In the present study, a new aqueous Al(III)-quinic complex was synthesized. The new species was characterized by elemental analysis, spectroscopic, and structural by X-ray analysis. Detailed aqueous speciation studies in the Al(III)-quinic system suggest the presence of a number of species, among which is the mononuclear [Al(C7H11O6)3]0 complex.
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